帶甲基側鏈手性試劑是一類新型手性合成試劑，廣泛存在于具有生物活性的天然產物分子中，帶甲基側鏈手性試劑可替代傳統的香茅醛/香茅醇類的手性試劑，是合成具有特殊生物活性的天然產物和藥物分子的重要手性原料，如抗腫瘤類醫藥[1,2]、群柱蟲內酯Clavulactone及其類似物[3]、昆蟲型信息素[4,5,6]、香料等，是近年來比較熱門的一類手性合成試劑。
百靈威可提供全新帶甲基側鏈手性試劑產品，化學純度及光學純度高，現貨供應，助力醫藥、香料合成化學家快速、有效地解決具有特殊生理活性天然復雜分子內多個手性構筑的大難題！
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產品編號
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產品名稱
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結構式
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規格
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CAS
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(R)-3-((R)-2,2-二甲基-1,3-二氧五環-4-基)-2-甲基-1-丙醇
(R)-3-((R)-2,2-Dimethyl-1,3-dioxolan-4-yl)-2-methylpropan-1-ol
95% [ee: 98%]
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1 g
5 g
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(R)-5-芐氧基-4-甲基-2-氧-戊酸甲酯
(R)-5-Benzyloxy-4-methyl-2-oxo-methyl pentanoate
95% [ee: 98%]
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1 g
5 g
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(R)-4-芐氧基-3-甲基丁腈
(R)-4-Benzyloxy-3-methylbutyronitrile
98% [ee: 98%]
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1 g
5 g
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Reference:
[1] McKenna, Jeffrey; et al. Assignee Signal Pharmaceuticals, LLC, USA 2007.
[2] Tian, Weisheng; . et. al. Peop. Rep.China 2011
[3] By Zhu, Qiang ; et al.Journal of Organic Chemistry (2001), 66(8), 2692-2699.
[4] Coppel, H. C. et al Science 1976, 192, 51.
[5] Hedenström, E. et al Tetrahedron 1992, 48, 3139.
[6] Wang Z.K. et. al Tetrahedron Lett., 2007, 48, 7549
◆手性輔助劑
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產品編號
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產品名稱
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結構式
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規格
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CAS
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(R)-(-)-4-Benzyl-3-propionyl-2-
oxazolidinone, 99% ee:99%
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1 g
5 g
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(S)-4-Benzylthiazolidine-2-thione,
99% ee: 99%
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250 mg
1 g
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R-tert-Butylsulfinamide, 98%
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1 g
5 g
25 g
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(R)-(+)-5,5-Diphenyl-4-benzyl-2-
oxazolidinone, 98%, ee:98%
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100 mg 500 mg
1 g
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(R)-(+)-5,5-Diphenyl-4-methyl-2-
oxazolidinone, 97%
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100 mg 500 mg
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(4R,5S)-(+)-cis-4,5-Diphenyl-2-
oxazolidinone, 98%, ee:98%
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100 mg 500 mg
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(R)-(-)-4-(1H-Indol-3-ylmethyl)-2-
oxazolidinone, 98%,ee: 98%
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100 mg 500 mg
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(S)-(-)-4-Isopropyl-5,5-diphenyl-2-
oxazolidinone, 98%, ee: 99%
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1 g
5 g
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(S)-(+)-4-Isopropyl-3-propionyl-2-
oxazolidinone, 98%, ee: 98%
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1 g
5 g
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